报告人：黄礼荣研究员(华南理工大学)

报告题目： Reconstructing dynamic molecular states from single-cell time series

报告摘要：For biomolecular reaction networks we show how to complete the partial state information accessible by experimental techniques into a full system state using mathematical analysis together with a computational model. We introduce the posterior master equation and derive novel approximation to the corresponding infinite-dimensional posterior moment dynamics. We exemplify this state reconstruction approach using both, in silico data and single-cell data from two gene expression systems in Saccharomyces cerevisiae, where we reconstruct the dynamic promoter and mRNA states from noisy protein abundance measurements.

报告时间：2017年11月15日(星期三)上午：11:00-12:00

报告地点：科技楼(南楼)602